Si toma diazepam junto con otros medicamentos para controlar las convulsiones, no deje de tomar diazepam sin consultarlo antes con su médico, incluso si experimenta efectos secundarios como cambios inusuales en el comportamiento o estado de ánimo.
Check Closely (one)levonorgestrel oral/ethinylestradiol/ferrous bisglycinate will increase the level or effect of diazepam by decreasing metabolism.
stiripentol will lessen the extent or impact of diazepam by impacting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Watch Intently. Think about lessening the dose of CYP2C19 substrates, if adverse reactions are seasoned when administered concomitantly with stiripentol.
cobicistat will raise the level or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. A lessened dose of diazepam could possibly be essential
diazepam and daridorexant both of those maximize sedation. Modify Therapy/Check Intently. Coadministration increases chance of CNS despair, which can result in additive impairment of psychomotor overall performance and lead to daytime impairment.
Paradoxical reactions may perhaps occur including hallucinations, intense conduct, and psychoses; dinscontinue use if reactions manifest
VALIUM could make you sleepy or dizzy, and can gradual your thinking and motor expertise. Will not generate, operate significant machinery, or do other unsafe routines until finally you know how VALIUM impacts you.
Lonafarnib could improve the AUC and peak focus of CYP2C19 substrates. If coadministration unavoidable, check for adverse reactions and lessen the CYP2C19 substrate dose in accordance with its authorized solution more info labeling.
aprepitant will improve the stage or impact of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.
The above mentioned data is delivered for normal informational and educational reasons only. Unique plans could range and formulary data alterations. Make contact with the relevant system supplier for one of the most present information.
บทความเภสัชกรรมและยานี้ยังเป็นโครง คุณสามารถช่วยวิกิพีเดียได้โดยการเพิ่มเติมข้อมูล
A TPSA worth of 32,7 Ų signifies a average volume of polarity in the compound. TPSA is very valuable in clinical chemistry because it reveals the flexibility of the molecule to permeate cells. Molecules with PSA worth smaller than sixty-70 Ų have a greater power to permeate cells.[27] The harmony involving its lipophilic and hydrophilic features can effects many components of the molecule’s behavior, including its solubility, absorption, distribution, metabolism, and probable interactions within the biological program.
Los medicamentos que ya no son necesarios se deben desechar de una manera apropiada para asegurarse de que las mascotas, los niños y otras personas no puedan consumirlos. Sin embargo, no debe desechar estos medicamentos por el inodoro. En su lugar, la mejor manera de deshacerse de sus medicamentos es a través de un programa de devolución de medicamentos.
darifenacin will raise the amount or influence of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.